Points to Consider for Operation and Management to Ensure the Reliability of Registry Data for Use in Application Dossiers of Pharmaceuticals and Medical Devices Hideki Oi,et al. Subgroup for “Review of the quality management system and points to consider”
■BRIEF REPORT Use of Electronic Consent Forms in an Observational Pilot Study of Coronavirus Disease in Japan Jia Yu Yasuhito Imai Akihiro Nomura Takashi Yoneda Toshinori Murayama
■ORIGINAL ARTICLES Effects of glucose-dependent insulinotropic polypeptide(GIP)on RANKL and type 1 collagen in triglyceride-rich lipoproteins-loaded osteoblasts Mieko Saito, et al.
Effects of dietary intake of food containing kale(Brassica oleracea var. acephala)on antioxidant capacity in humans ―A randomized, placebo-controlled, double-blind, parallel-group study― Sumio Kondo, et al.
■BRIEF COMMUNICATION Feeding edible bird’s nest extract to ovariectomized rats downregulates the mRNA expression of RANKL in their femurs Shinya Masuda, et al.
Effect of kiwifruit-derived procyanidins with lipid absorption inhibitory action on body composition-improvement ―A randomized, double-blind, placebo-controlled, parallel-group comparative trial― Nozomi Isomura, et al.
■REVIEWS Assessment of in vitro, in vivo, and clinical safety of SIRTMAX(R) a standardized Kaempferia parviflora rhizome extract Chin Piow Wong, et al.
Effect of oral intake of Lactobacillus acidophilus L-92 on systemic and intestinal immune parameters ―A randomized, double-blind, placebo-controlled, parallel-group trial― Masaki Sasai, et al.
Collagen absorption-promoting effects of maltobionic acid and calcium maltobionate in healthy Japanese adult men and women ―A randomized double-blind placebo-controlled crossover study― Daiki Suehiro, et al.
Reduction of visceral fat and blood glucose in overweight women by compound phytostenone cream ―A randomized double-blind parallel-group study― Tadashi Nagashima, et al.
■TOPIC 第21回CRCと臨床試験のあり方を考える会議 2021 in 横浜 <受賞演題> 大阪臨床研究ネットワーク(OCR-net)を活用した脳卒中領域の臨床研究支援 大阪大学医学部附属病院 岩本 穂珠美ほか
■ORIGINAL ARTICLES Characterization of the relationship between the pharmacokinetics of tolvaptan and the pharmacodynamic effects on urine volume after single and multiple doses of intravenous OPC-61815 and oral tolvaptan ―A population pharmacokinetic/pharmacodynamic model― Masatoshi Masuda, et al.
Impacts of salmon nasal cartilage-derived proteoglycans on the skin properties in Japanese adult women ―A randomized, placebo-controlled, double-blind, parallel-group comparison study― Tatsuya Wada, et al.
The effect of soy peptide intake on sarcopenia and cognitive decline in community-dwelling older adults ―A randomized controlled trial― Motohiro Maebuchi, et al.
Safety of long-term administration of a systemic-acting diclofenac sodium patch(HP-3150)in Japanese patients with low back pain Toshihiko Taguchi, et al.
Effects of kaki-tannin on reducing serum LDL cholesterol levels in volunteers with borderline and mild hyper-LDL cholestrolemia ―A randomized, double-blind, placebo-controlled, parallel-group comparison trial― Toshio Suzuki, et al.
Single administration of taxifolin-rich extract to young adults improves their sequential single task performance ―A randomized, placebo-controlled, double-blind, crossover trial― Fumika Shinozaki, et al.
Effects of bovine lactoferrin on subjective gastrointestinal symptoms related to physical conditions in healthy subjects ―A randomized, double-blind, placebo-controlled trial― Momoko Miyakawa, et al.
The effect of S-allylcysteine enriched garlic extract on mental fatigue ―A randomized, double-blind, placebo-controlled, parallel, comparative clinical study― Naoyuki Matsunaga, et al.